How should biological samples be stored after collection until submission to the toxicologist?

How should biological samples be stored after collection until submission to the toxicologist?

• A. At room temperature
• B. In a freezer
• C. In a refrigerator
• D. Under direct sunlight

Answer: (C)

Storing biological samples properly is crucial for maintaining their integrity before analysis by a toxicologist. Keeping samples in a refrigerator is the best practice because it slows down the degradation of biological materials and minimizes the growth of potential microbial contaminants. By maintaining a stable, cool temperature, the biochemical processes that can alter the composition of the samples are significantly slowed, ensuring that the samples remain representative of the individual's biological state at the time of collection. When considering other storage methods, storing at room temperature can lead to rapid degradation and changes in the samples, which would negatively affect the results of toxicological analyses. A freezer may be appropriate for certain types of samples, but not all biological samples tolerate freezing well, as freezing can cause cell lysis and alter the concentration of certain substances. Additionally, storing samples under direct sunlight can cause photodegradation and other chemical changes, leading to compromised results. Therefore, refrigeration is the optimal choice for storing biological samples prior to submission for testing.

Storing biological samples properly is crucial for maintaining their integrity before analysis by a toxicologist. Keeping samples in a refrigerator is the best practice because it slows down the degradation of biological materials and minimizes the growth of potential microbial contaminants. By maintaining a stable, cool temperature, the biochemical processes that can alter the composition of the samples are significantly slowed, ensuring that the samples remain representative of the individual's biological state at the time of collection.

When considering other storage methods, storing at room temperature can lead to rapid degradation and changes in the samples, which would negatively affect the results of toxicological analyses. A freezer may be appropriate for certain types of samples, but not all biological samples tolerate freezing well, as freezing can cause cell lysis and alter the concentration of certain substances. Additionally, storing samples under direct sunlight can cause photodegradation and other chemical changes, leading to compromised results. Therefore, refrigeration is the optimal choice for storing biological samples prior to submission for testing.